Human Biology & BioImaging
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Publications

Karg E, Smets M, Ryan J, Forné I, Qin W, Mulholland CB, Kalideris G, Imhof A, Bultmann S and Leonhardt H (2017). Ubiquitome analysis reveals PCNA-associated factor 15 (PAF15) as a specific ubiquitination target of UHRF1 in embryonic stem cells. J Mol Biol., 2017 Oct 18. [Epub ahead of print] PubMed

Dahlhoff M, Gaborit N, Bultmann S, Leonhardt H, Yarden Y and Schneider MR (2017). CRISPR-assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes. FEBS J., 284, 3339-3349.PubMed

Mazaheri F, Snaidero N, Kleinberger G, Madore C, Daria A, Werner G, Krasemann S, Capell A, Trümbach D, Wurst W, Brunner B, Bultmann S, Tahirovic S, Kerschensteiner M, Misgeld T, Butovsky O and Haass C (2017). TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury. EMBO Rep., 18, 1186-1198. PubMed

Anton T and Bultmann S (2017). Site-specific recruitment of epigenetic factors with a modular CRISPR/Cas system. Nucleus, 8, 279-286. PubMed

Sellou H, Lebeaupin T, Chapuis C, Smith R, Hegele A, Singh HR, Kozlowski M, Bultmann S, Ladurner AG, Timinszky G and Huet S (2016). The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage. Mol Biol Cell, 27, 3791-3799. PubMed

Mulholland CB, Smets M, Schmidtmann E, Leidescher S, Markaki Y, Hofweber M, Qin W, Manzo M, Kremmer E, Thanisch K, Bauer C, Rombaut P, Herzog F, Leonhardt H and Bultmann S (2015). A modular open platform for systematic functional studies under physiological conditions. Nucleic Acids Res., 43, e112. PubMed

Feodorova Y, Koch M, Bultmann S, Michalakis S and Solovei I (2015). Quick and reliable method for retina dissociation and separation of rod photoreceptor perikarya from adult mice. MethodsX, 2, 39-46. PubMed

Anton T, Bultmann S, Leonhardt H and Markaki Y (2014). Visualization of specific DNA sequences in living mouse embryonic stem cells with a programmable fluorescent CRISPR/Cas system. Nucleus, 5, 163-172. PubMed

Thanisch K, Schneider K, Morbitzer R, Solovei I, Lahaye T, Bultmann S and Leonhardt H (2013). Targeting and tracing of specific DNA sequences with dTALEs in living cells. Nucleic Acids Res., 42(6): e38. PubMed

Bultmann S and Leonhardt H (2013). Fluorescence microscopy-based high-throughput screening for factors involved in gene silencing. Methods Mol Biol, 1042, 237-44. PubMed

Schmidt CS, Bultmann S, Meilinger D, Zacher B, Tresch A, Maier KC, Peter C, Martin DE, Leonhardt H and Spada F (2012). Global DNA Hypomethylation Prevents Consolidation of Differentiation Programs and Allows Reversion to the Embryonic Stem Cell State. PLoS One, 2012 Dec 27, e52629. PubMed

Bultmann S, Morbitzer R, Schmidt CS, Thanisch K, Spada F, Elsaesser J, Lahaye T and Leonhardt H (2012). Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers. Nucleic Acids Res., 40, 5368-77. PubMed

Frauer C, Hoffmann T, Bultmann S, Casa V, Cardoso MC, Antes I and Leonhardt H (2011). Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain. PLoS ONE, 6, e21306. PubMed

Konstandin N, Bultmann S, Szwagierczak A, Dufour A, Ksienzyk B, Schneider F, Herold T, Mulaw M, Kakadia PM, Schneider S, Spiekermann K, Leonhardt H and Bohlander SK (2011). Genomic 5-hydroxymethylcytosine levels correlate with TET2 and IDH2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia. Leukemia, 25, 1649-52. PubMed

Szwagierczak A, Brachmann A, Schmidt CS, Bultmann S, Leonhardt H and Spada F (2011). Characterization of PvuRts1I endonuclease as a tool to investigate genomic 5 hydroxymethylcytosine. Nucl. Acids Res., 39, 5149-56.   PubMed

Frauer C, Rottach A, Meilinger D, Bultmann S, Fellinger K, Hasenöder S, Wang M, Qin W, Söding J, Spada F and Leonhardt H (2011). Different Binding Properties and Function of CXXC Zinc Finger Domains in Dnmt1 and Tet1. PLoS ONE, 6, e16627. PubMed

Szwagierczak A, Bultmann S, Schmidt CS, Spada F and Leonhardt H (2010). Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA. Nucl. Acids Res., 38, e181. PubMed

Meilinger D, Fellinger K, Bultmann S, Rothbauer U, Bonapace IM, Klinkert WE, Spada F and Leonhardt H (2009). Np95 interacts with de novo DNA methyltransferases Dnmt3a and 3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells. EMBO Reports, 10, 1259-64. PubMed