Publications

Steinek C, Guirao-Ortiz M, Stumberger G, Tölke AJ, Hörl D, Carell T, Harz H and Leonhardt H (2024). Generation of densely labeled oligonucleotides for the detection of small genomic elements. Cell Rep Methods, 4, 100840. PubMed

Zülske T, Attou A, Groß L, Hörl D, Harz H and Wedemann G (2024). Nucleosome spacing controls chromatin spatial structure and accessibility. Biophys J., 123, 847-857. PubMed

Bachem K, Li X, Ceolin S, Mühling B, Hörl D, Harz H, Leonhardt H, Arnoult L, Weber S, Matarlo B, Prud'homme B and Gompel N (2024). Regulatory evolution tuning pigmentation intensity quantitatively in Drosophila. Sci Adv., 10, eadl2616. PubMed

Palikyras S, Sofiadis K, Stavropoulou A, Danieli-Mackay A, Varamogianni-Mamatsi V, Hörl D, Nasiscionyte S, Zhu Y, Papadionysiou I, Papadakis A, Josipovic N, Zirkel A, O'Connell A, Loughran G, Keane J, Michel A, Wagner W, Beyer A, Harz H, Leonhardt H, Lukinavicius G, Nikolaou C and Papantonis A (2024). Rapid and synchronous chemical induction of replicative-like senescence via a small molecule inhibitor. Aging Cell, 9, e14083. PubMed

Bunk D, Moriasy J, Thoma F, Jakubke C, Osman C and Hörl D (2022). YeastMate: Neural network-assisted segmentation of mating and budding events in S. cerevisiae. Bioinformatics, 38, 2667-2669. PubMed

Brandstetter K, Zülske T, Ragoczy T, Hörl D, Guirao-Ortiz M, Steinek C, Barnes T, Stumberger G, Schwach J, Haugen E, Rynes E, Korber P, Stamatoyannopoulos JA, Leonhardt H, Wedemann G and Harz H (2022). Differences in nanoscale organization of regulatory active and inactive human chromatin. Biophys J., 121, 977-990. PubMed

Jakubke C, Roussou R, Maiser A, Schug C, Thoma F, Bunk D, Hörl D, Leonhardt H, Walter P, Klecker T and Osman C (2021). Cristae-dependent quality control of the mitochondrial genome. Sci Adv., 7, eabi8886. PubMed

Le Poul Y, Xin Y, Ling L, Mühling B, Jaenichen R, Hörl D, Bunk D, Harz H, Leonhardt H, Wang Y, Osipova E, Museridze M, Dharmadhikari D, Murphy E, Rohs R, Preibisch S, Prud’homme B and Gompel N (2020). Regulatory encoding of quantitative variation in spatial activity of a Drosophila enhancer. Sci. Adv., 6, eabe2955. PubMed

Rausch C, Weber P, Prorok P, Hörl D, Maiser A, Lehmkuhl A, Chagin V, Casas-Delucchi CS, Leonhardt H and Cardoso MC (2020). Developmental differences in genome replication program and origin activation. Nucleic Acids Res., 48, 12751-12777. PubMed

Hörl D, Rojas Rusak F, Preusser F, Tillberg P, Randel N, Chhetri RK, Cardona A, Keller PJ, Harz H, Leonhardt H, Treier M and Preibisch S (2019). BigStitcher: Reconstructing high-resolution image datasets of cleared and expanded samples. Nature Methods, 16, 870-874. PubMed

Natale F, Rapp A, Yu W, Maiser A, Harz H, Scholl A, Grulich S, Anton T, Hörl D, Chen W, Durante M, Taucher-Scholz G, Leonhardt H and Cardoso MC (2017). Identification of the elementary structural units of the DNA damage response. Nat Commun., 8, 15760. PubMed

Schueder F, Strauss MT, Hoerl D, Schnitzbauer J, Schlichthaerle T, Strauss S, Yin P, Harz H, Leonhardt H and Jungmann R (2017). Universal Super-Resolution Multiplexing by DNA Exchange. Angew Chem Int Ed Engl., 56, 4052-4055. PubMed

Stengl A, Hörl D, Leonhardt H and Helma J (2017). A Simple and Sensitive High-Content Assay for the Characterization of Antiproliferative Therapeutic Antibodies. SLAS Discov., 22, 309-315. PubMed

Qin W, Wolf P, Liu N, Link S, Smets M, Mastra F, Forné I, Pichler G, Hörl D, Fellinger K, Spada F, Bonapace IM, Imhof A, Harz H and Leonhardt H (2015). DNA methylation requires a DNMT1 ubiquitin interacting motif (UIM) and histone ubiquitination. Cell Res., 25, 911-29. PubMed